BRMs Biologic Response Modifiers
Although the BRMs work in different ways, all inhibit proteins called cytokines, which contribute to inflammation. Adalimumab (Humira), etanercept (Enbrel) and infliximab (Remicade) block a cytokine called tumor necrosis factor- alpha (TNF-a); anakinra (Kineret) blocks a cytokine called interleukin-1 (IL-1).
Like many drugs, BRMs have a downside, most often, expense. Also, the drugs must be infused intravenously or injected. Researchers say that future agents may be less expensive and taken orally.
Arthritis News
Arthritis of the spine often overlooked in children
When kids or teens experience aching joints and stiffness it may be more than growing pains. It may be arthritis of the spine and other joints (ankylosing spondylitis), which researchers report can of...
A common sulfur-containing dietary supplement can help ease pain and improve physical function in patients with arthritic knees, according to a new study from Arizona researchers. The researchers g...
Cytokines swing between good and bad in the war on autoimmune arthritis
Rheumatoid arthritis (RA) is an autoimmune disease that targets the bone and cartilage. The cytokines BLyS and APRIL are present in the serum of RA patients. In a paper appearing online on October 20 ...
