BRMs Biologic Response Modifiers
Although the BRMs work in different ways, all inhibit proteins called cytokines, which contribute to inflammation. Adalimumab (Humira), etanercept (Enbrel) and infliximab (Remicade) block a cytokine called tumor necrosis factor- alpha (TNF-a); anakinra (Kineret) blocks a cytokine called interleukin-1 (IL-1).
Like many drugs, BRMs have a downside, most often, expense. Also, the drugs must be infused intravenously or injected. Researchers say that future agents may be less expensive and taken orally.
Arthritis News
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